Hi there, 
  
   I have 2 desktops, which are different hardware configuration, are running Vista 64bit. They both have the same problem that the DVD-rom disappeared suddenly. Before, I installed Window with those DVD Drives on both, they were working fine for a while after Window installed. Now, they do not show up in File Explorer as well as in Computer Management under Disk Management. I removed the DVD rom drive and tried in the other computer, it works fine. Checking cable connection is connected properly. That means the DVD drive is no problem.
   So, something wrong with Vista or what? Please help!

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