Keep in mind that there are no human studies showing any life extension
advantages for CR and the health effects for both humans and animals seem
very poor on the whole.  The non-CR animals seem to rate far superior in
every category but life span e.g. Cognitive function is impaired, puberty is
greatly delayed, menses is skipped.  And from my understanding, all of the
animal studies show that the life extension 'benefits' (!) are only attained
with a life long commitment to CR starting in adolecence.

Fagin draws his conclusions from MOUNTAINS of research using human studies
and biochemistry.

What is there to debate?

   Wade

-----Original Message-----
Richard Geller wrote:
This seems to contradict Faigin's thesis quite completely.

And as I said, how does catabolic metabolism connect with symptoms of
aging that may be outwardly similar?

--Richard

Todd Moody wrote:
> Richard Geller wrote:
>
>> Yet, people on CR seem to have their aging benchmarks slowed down.
>> Presumably they are in a catabolic state quite often?
>
>
>
> Yes, and animal studies indicate the same effect from infrequent feeding
> but with little or no CR; e.g., rats allowed to eat ad libitum every
> other day or once a day for a limited period of time.
>
> An interesting question is whether ketosis accelerates aging, however.
> I recall research indicating that ketosis produces substantial free
> radicals.  CR need not involve ketsosis much of the time.
>