"Vaccine Delivered by Fork, Not Needle"
New York Times (www.nytimes.com) (05/14/00) P. 26; Pollack,
Andrew

The edible vaccine underwent some of its first clinical trials
last year in Baltimore.  Scientists are seeking ways to deliver
vaccines through eating bananas, tomato paste, or crackers.  John
Howard, chief executive of ProdiGene, is working on an edible
vaccine in corn, which would be useful in developing countries.
Dr. Hilary Koprowski of Thomas Jefferson University and
scientists in Poland have made a hepatitis B vaccine found in
lettuce.  It is important the foods chosen be eaten raw, and
scientists hope to create an edible vaccine that requires no
refrigeration.  The edible vaccine would also make it easier on
children who refuse needles.