If HDL cholesterol is a concern it looks as if a high vegetable diet might 
inadvertently lower it. Theola, did you increase you veggie intake when you 
changed from Atkins/Eades to Paleo. I probably have access to the whole 
article going through CSUN, but it's such a chore. For what it's worth:

J Nutr 2002 Oct;132(10):3012-7   
  
Dietary modifications and gene polymorphisms alter serum paraoxonase activity 
in healthy women.

Rantala M, Silaste ML, Tuominen A, Kaikkonen J, Salonen JT, Alfthan G, Aro A, 
Kesaniemi YA.

Department of Internal Medicine and Biocenter Oulu, University of Oulu, 
Finland.

Paraoxonase-1 (PON1), a HDL-associated enzyme, may protect against the 
development of atherosclerosis. Serum PON1 activity and PON1-mediated 
capacity of HDL to prevent lipoprotein oxidation are modulated by two common 
polymorphisms at positions 192 (Gln-->Arg) and 55 (Leu-->Met) of the PON1 
gene. We studied the effect of dietary modifications on PON1 activity and the 
role of PON1 gene polymorphisms in the response. A controlled, crossover 
dietary intervention of two 5-wk periods was conducted in 37 healthy, 
nonsmoking women. The two study diets were either low or high in vegetables, 
and thus in natural antioxidants, with some differences in fatty acid 
contents. The mean plasma total (-8%, P < 0.001), LDL (-7%, P < 0.01) and HDL 
(-7%, P < 0.001%) cholesterol, and apolipoprotein A-I (-8%, P < 0.001) 
concentrations were lower after the high vegetable diet period than after the 
low vegetable diet period. Also, the serum PON1 activity was lower (P < 0.05) 
after the high vegetable compared with the low vegetable diet period. The 
reduction of PON1 activity correlated with the reduction in HDL cholesterol 
(r = 0.35, P < 0.05). High baseline PON1 activity was related to the presence 
of the PON1(192Arg) allele (P < 0.001) and PON1(55Leu/Leu) genotype (P < 
0.001). The reduction of PON1 activity due to the high vegetable diet was 
greatest among the women with the PON1(192Arg) allele (P < 0.05) and 
PON1(55Leu/Leu) genotype (P < 0.05). In conclusion, a diet high in 
vegetables, berries and fruit reduces PON1 activity, and the response is 
modulated by the genetic variance of PON1.



Namaste, Liz
<A HREF="http://www.csun.edu/~ecm59556/Healthycarb/index.html">
http://www.csun.edu/~ecm59556/Healthycarb/index.html</A>