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From:
R Bartlett <[log in to unmask]>
Reply To:
Paleolithic Eating Support List <[log in to unmask]>
Date:
Sun, 13 May 2001 17:46:29 -0700
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<<But read up on hyperinsulinimia and insulin resistance before reaching
conclusions>>

Here's a good overview:

"Today, each of the stages in the progression of Insulin Resistance Syndrome
has been described and studied, and though you might not be a scientist, if
you are addicted to [carbs], chances are you have experienced some of these
stages firsthand.  The cells in your brain and the rest of the nervous
system appear to be the first to become insulin resistant.  In order to
protect you from a flood of insulin, your body simply closes these cells
down (that is, it makes them resistant to insulin).  Unfortunately, when the
doors to the cells in your brain and nervous system close to insulin, they
also close to the blood sugar that insulin ushers in and that would normally
nourish them.

The First Stage of Insulin Resistance Syndrome [IRS]

In this first stage of [IRS], you may find that within two hours after
eating high-[carb] foods, you feel light-headed, irritable, or unable to
concentrate.  In addition to craving high-[carb] foods, you may gain weight
easily as an increased quantity of the food energy (transformed into blood
sugar ) is channeled through the liver, turned into blood fat, then stored
in your fat cells.

The Second Stage of Insulin Resistance Syndrome [IRS]

If hyperinsulinemia continues, a second stage of [IRS] may occur, and the
postmeal cravings, tiredness, light-headedness, irritability, or inability
to concentrate that you felt before may become more noticeable.  Your
muscles, liver, and other organs will likewise begin to block insulin's
entry and, in doing so, will also close off their ability to get nourishment
from blood sugar.  As muscles experience a decrease in blood sugar fueling,
you may experience a decrease in your desire or willingness to be active or
to exercise.  You might feel less inclined to do very much except what is
absolutely necessary.  If you do feel motivated to be active or find you
must be active, you may lose your desire to continue activity or find that
you tire easily.

In this second stage of [IRS], weight gain is almost inevitable, as food
energy (in the form of blood sugar transformed into blood fat) is channeled
increasingly into the fat cells for storage.  In addition to weight
problems, in particular abdominal obesity, the second stage of [IRS] can
herald a wide variety of noticeable heart disease risk factors, including an
increase in risk-related blood fats, increases in blood pressure levels, and
more.

During both the first and second stages, insulin is able to continue to
usher some blood sugar into the cells of many organs, but if no corrective
action is taken, these cells will grow more and more insulin resistant,
closing the doors (or sites) through which blood sugar had previously
entered.  The liver, sensitive to these high levels or insulin and blood
sugar in the bloodstream, transforms the excess blood sugar into blood fat
so that it can be removed from the blood, and the blood sugar (now in the
form of fat) is stored in the fat cells.  In the first two stages of [IRS],
then, as insulin resistance grows, insulin has transformed your body into a
fat-making machine.  As the cells of many organs throughout your body become
insulin resistant, your fat cells become the preferred storage site for
blood sugar.

The Third Stage of Insulin Resistance Syndrome [IRS]

In the third stage of [IRS], brain-related low blood sugar swings can become
severe, and your muscles may literally be starving for nourishment.  At this
stage you may
experience extreme mood swings, irritability, inability to concentrate,
tiredness, muscle shakes, depression, headaches, and foggy thinking.  You
may gain weight more easily than you ever thought possible and find that
cravings for starches, snack foods, junk foods, and sweets has become
uncontrollable.  Much of the weight you gain may be deposited as abdominal
or tummy fat.  Most likely, you find that you prefer frequent snacks rather
than typical mealtimes, and when you do snack or eat a meal, you may
continue to eat even though you are uncomfortable and/or no longer enjoy the
food.

The Fourth Stage of Insulin Resistance Syndrome [IRS]

Chances are, as you enter the  fourth stage of [IRS], you will no longer be
able to ignore or deny the physical changes that have sprung for your body's
insulin imbalance.  At this stage even your fat cells can become insulin
resistant and close down to insulin and to the blood sugar/blood fat it
brings along with it.  Many of the symptoms you experienced at earlier
stages in the progression reach a peak in the fourth stage, with the
significant exception of low blood sugar and weight gain.

Two of the signs of [IRS], rising blood sugar levels and weight gain,
reverse in the fourth stage.  At this final level, even fat cells closedown.
Now insulin, blood sugar, and blood fat are caught with no place to go. They
cannot leave the bloodstream and remain blocked there.  So in this final
stage, rather than channeling the energy into fat cells, leading to weight
gain, your body may no longer be able to channel energy into your fat
cells, and your weight may suddenly drop a bit (though usually not to normal
levels).

In the same way, the low blood sugar swings that you might have experienced
when blood sugar and blood fat are being channeled into your fat cells in
the third stage will disappear and be replaced by high levels of blood
sugar.  At this point, as blood sugar is trapped in your bloodstream, unable
to enter the organs or to be converted and then stored as fat in your fat
cells, you may be said to have adult-onset diabetes."

source:  The Carbohydrate Addict's Healthy Heart Program, p56-60

Rob

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