Comments?

Article at: http://www.sciencedaily.com/releases/2002/02/020221072854.htm
Source:   Kansas State University (http://www.ksu.edu/)

Date:   Posted 2/22/2002

Wheat May Be Vital In Battle Against Cancer And Other Diseases

MANHATTAN — A new weapon has been discovered in the battle against disease:
whole grain wheat.
According to Kansas State University biochemist Dolores Takemoto, new research
is showing that wheat contains powerful antioxidants which are key to its
ability to prevent colon cancer, and possibly diabetes and heart disease.

"In the past, we thought the fiber in wheat prevented cancer," Takemoto said.
"This discovery shows that there are antioxidants, in addition to fiber, which
are responsible for preventing cancer."

With this information, K-State scientists maybe be able to create modified wheat
strains with high levels of cancer-fighting chemicals.

"We hope we will be able to create a genetically modified plant," Takemoto said.
"We won't be modifying it to adapt to its environment, like most genetically
modified plants, but we will be modifying it to produce more of its own
cancer-fighting chemicals. We want to produce for the Kansas community strains
of wheat that are nutraceuticals, which are higher quality grains that have
enhanced amounts of these antioxidants in them."

Wheat's antioxidants are important because they combat the body's free-radicals.
Free-radicals are charged particles which the body produces and which, if they
react harmfully, could cause damage.

"Throughout life you make a lot of free-radicals," Takemoto said. "You want to
keep them from forming because they contribute to heart disease, cancer,
diabetes, cataracts, even wrinkling. High antioxidant levels mop up the
free-radicals."

Wheat's antioxidants are found in the plant's orthophenols. Takemoto and other
K-State biochemists are in the early stages of developing wheat with high levels
of orthophenols. A successful modification could lead to wheat's ability to
combat cancer by simply including it in a daily diet.

K-State scientists are optimistic of wheat's cancer-fighting ability because
their preliminary testing shows some available wheat strains already contain a
great number of orthophenols.

"Several high antioxidant wheat strains are already available for growing,"
Takemoto said. "People worry about the antioxidants not surviving baking, but
some of the strains we tested had high antioxidant levels across the board.
These could be grown now and they do survive baking well."

Antioxidants can be found in several vitamins, including vitamin E and vitamin
D, but research shows that eating whole grain products and wheat germ is
critical for the antioxidants to be absorbed.

"I like to argue against taking a pill," Takemoto said. "Only very stable
vitamins provide the high levels of antioxidants needed, and even then they
don't have very long shelf lives. Folic acid, for example, doesn't have a long
shelf life for keeping high antioxidant levels. Many people use vitamin pills to
compensate for a poor diet, but including whole grain wheat into your regular
diet will have greater effects."

This project is funded by the Kansas Wheat Commission. Takemoto received her
doctoral degree from the University of Southern California. She has been
teaching and conducting research at K-State for 23 years.