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From:
ken barber <[log in to unmask]>
Reply To:
Date:
Sat, 9 Aug 2008 11:31:07 -0700
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my mom was sick quite a bit when carrying me and i was 8 weeks early. 


--- On Wed, 7/30/08, greta von der luft <[log in to unmask]> wrote:

> From: greta von der luft <[log in to unmask]>
> Subject: Re: Genetic Link to CP??
> To: [log in to unmask]
> Date: Wednesday, July 30, 2008, 4:55 PM
> I have some strange interests and one them is trying to keep
> up to date on
> the pathophysiology and etiology of CP. Some of the causes
> of CP that I am
> familiar with include:
> 
>    - mom having an increased risk of bleeding (type of
> hemophilia) or
>    clotting during her pregnancy.
>    - mom having an bacterial infection/virus during her
> pregnancy causing a
>    spike in temperature
>    - mom having a viral/bacterial infection in her birth
> canal at the time
>    of birth
>    - mom having increased stress during her pregnancy
> (particulary if she
>    lives in an area of high crime/violence/tension)
>    - mom having a poor diet during her pregnancy
>    - mom having a poorly defined placenta and blood supply
> to the
>    embryo/fetus
> 
> All of these except for the diet can cause a change in the
> fetal/embryo/neonate's heart rate and blood pressure
> which then can cause
> the "brain injury" (aka static encephalopathy)
> that is commonly found in
> people with cerebral palsy.
> 
> However, in premature infants there is an artery called the
> Heubner artery
> near the fourth ventricle in the brain which does not have
> good collateral
> (replacement circulation if needed) that is very vulnerable
> to injury from
> changes in BP and HR. If this area is compromised by these
> changes the nerve
> fibers for the legs are affected. If there is a sinificant
> affect/damage
> here then the trunk and arm fibers are affected.
> 
> Here ends the anatomy lesson...I have not heard of genetic
> causes of CP...
> 
> Take care and hope everyone is having a great summer.
> 
> Greta
> 
> Here
> On Wed, Jul 30, 2008 at 1:45 PM, Kendall D. Corbett <
> [log in to unmask]> wrote:
> 
> > Linda,
> >
> > Sounds like a plausible explanation of some cases of
> CP, but many,
> > if not most are caused by birth trauma and premature
> birth.
> >
> > On Wed, Jul 30, 2008 at 12:22 PM, Linda Macaulay
> <[log in to unmask]
> > >wrote:
> >
> > > Here's something I found on BabyCenter --
> take a look!
> > >
> > > Australian study seeks genetic roots of cerebral
> palsy
> > >
> > >
> http://www.babycenter.com/204_australian-study-seeks-genetic-roots-of-
> > > cerebral-palsy_5234805.bc
> > > (If clicking doesn't work, simply cut and
> paste the link into your Web
> > > browser.)
> > >
> > >
> > > When I first saw the title, I thought "No
> way!", but then in reading it,
> > > maybe...
> > >
> > > Heck, my mom and I both have Factor V Leiden
> which is a genetic mutation
> > to
> > > be more prone to blood clots.  When we learned I
> had it and then mom too,
> > we
> > > realized that was probably why she had so many
> miscarriages and that I
> > came
> > > early...placenta bloodclotting...thus why I must
> take injections of blood
> > > thinner when pregnant and be monitored closely...
> > >
> > > Any thoughts?
> > >
> > > Linda
> > >
> > > -----------------------
> > >
> > > To change your mail settings or leave the C-PALSY
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> > >
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> > >
> >
> >
> >
> > --
> >
> >
> > Kendall
> >
> > An unreasonable man (but my wife says that's
> redundant!)
> >
> > The reasonable man adapts himself to the world; the
> unreasonable one
> > persists in trying to adapt the world to himself.
> Therefore, all progress
> > depends on the unreasonable man.
> >
> > -George Bernard Shaw 1856-1950
> >
> > -----------------------
> >
> > To change your mail settings or leave the C-PALSY
> list, go here:
> >
> >
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> >
> 
> -----------------------
> 
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