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Date: | Mon, 9 Jul 2001 06:39:53 -0700 |
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Cancer does indeed occur in wild animals. Studying diseases of
wild animals is a specialty field in biology, and it has
at least one journal. Here's an abstract re: marine mammals.
1. Gauthier, J. M.; Dubeau, H.; Rassart, E.; Jarman, W. M.; Wells, R. S.
Biomarkers of DNA damage in marine mammals.
Mutation Research. Aug. 18, 1999. 444(2):427-439.
Abstract:
Certain environmental contaminants found in marine mammals have been shown
to cause DNA damage and cancer. The micronuclei (MN), sister chromatid
exchange (SCE) and/or chromosome aberration (CA) assays were used to assess
baseline (spontaneous) levels of DNA damage in blood lymphocytes of
individuals of the relatively healthy and lightly contaminated Arctic
beluga whale (Delphinapterus leucas), Sarasota Bay, FL, bottlenose dolphin
(Tursiops truncatus) and Northwestern Atlantic grey (Halichoerus grypus)
and harp (Phoca groenlandicus) seal populations. MN cell (MNC) frequencies
ranged between 2 and 14/1000 binucleated (BN) cells and were statistically
similar between species. In bottlenose dolphins, MNC frequency was
correlated with age and was significantly higher in females than in males.
No intraspecific variation in MNC frequency was found in beluga whales.
Intraspecific variation was riot tested in seals due to the small sample
size. Frequencies of SCEs and total CAs, excluding gaps, ranged,
respectively, between 1 and 15 SCE(s)/per cell and 4-6 CAs/100 cells in
beluga whales. SCE and CA frequencies did not vary with age or sex in
beluga whales. The MN, SCE and CA assays were found to be practical tools
for the detection of DNA damage in marine mammals and could be used in the
future to compare DNA damage between relatively lightly and highly
contaminated populations.
Tom Billings
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