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Raw Food Diet Support List <[log in to unmask]>
Subject:
From:
"Thomas E. Billings" <[log in to unmask]>
Date:
Thu, 27 May 2004 08:04:29 -0700
Reply-To:
Raw Food Diet Support List <[log in to unmask]>
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Previously I have posted citations for recently published scientific
articles showing that:

1. mtDNA analysis shows human genetic adaptation to different climates
and diets

2. Comparison of the human vs chimp genome shows humans are adapted to a
much higher protein intake than chimps, e.g., higher meat intake.

Here's yet more genetic evidence that humans are not natural "strict
vegetarians" -- the false claim promoted by certain raw pseudoscience
"experts"  (who, by the way,  lack scientific credentials and are fakes):

The Quarterly Review of Biology
Vol. 79          No. 1          March 2004

Abstract at:

http://www.journals.uchicago.edu/QRB/journal/issues/v79n1/790101/brief/790101.abstract.html

MEAT-ADAPTIVE GENES AND THE EVOLUTION OF SLOWER AGING IN HUMANS

CALEB E. FINCH
CRAIG B. STANFORD

ABSTRACT

The chimpanzee life span is shorter than that of humans, which is
consistent
with a faster schedule of aging. We consider aspects of diet that may have
selected for genes that allowed the evolution of longer human life spans
with
slower aging. Diet has changed remarkably during human evolution. All
direct
human ancestors are believed to have been largely herbivorous. Chimpanzees
eat
more meat than other great apes, but in captivity are sensitive to
hypercholesterolemia and vascular disease. We argue that this dietary shift
to
increased regular consumption of fatty animal tissues in the course of
hominid
evolution was mediated by selection for "meat-adaptive" genes. This
selection
conferred resistance to disease risks associated with meat eating also
increased
life expectancy. One candidate gene is apolipoprotein E (apoE), with the E3
allele
evolved in the genus Homo that reduces the risks for Alzheimer's and
vascular
disease, as well as influencing inflammation, infection, and neuronal
growth.
Other evolved genes mediate lipid metabolism and host defense. The timing
of the
evolution of apoE and other candidates for meat-adaptive genes is discussed
in
relation to key events in human evolution.

KEYWORDS
aging, apolipoprotein E, chimpanzee, diet, evolution, great apes, human,
hypercholesterolemia

Tom Billings

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