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Date: | Mon, 4 Sep 1995 13:12:04 -0400 |
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<<Disclaimer: Verify this information before applying it to your situation.>>
On Sept. 2nd, Bernie Mansback asked for a backup statement to a prior posting
about a B-12 deficiency relationship to MS. I don't know of a B-12
connection, but I did find an abstract on Medline concerning folic acid
deficiency that might be of interest to Bernie and also to William Estes who
asked on Sept. 3rd: " Does anyone know of an article on the WWW .... common
neurological side-effects of cd"
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Viader F, et al. Celiac disease in adults revealed by sensory-motor
neuropothy. Presse Med, 1995, Jan 28, Vol. 24, Pg: 222-4.
Central or peripheral nervous system complications are occasionally observed
in adult patients with celiac disease. Several mechanisms have been proposed
including vitamin deficiency, vascular inflammation and a direct effect of
gluten intolerance. Typical nerve fiber damage due to demyelinization has
been suggested. We observed a 65-year old woman with a right peroneal nerve
palsy superimposed on a diffuse peripheral neuropathy who was found to have
folic acid deficiency which in turn led to the diagnosis of adult celiac
disease. Electrophysiological and histological studies demonstrated a
predominantly demyelinating peripheral neuropathy which responded first to
parenteral folic acid supplementation and second to a gluten-free diet. The
mechanisms of peripheral nerve damage in adult celiac disease are briefly
discussed and the possible role of folic acid deficiency is emphasized.
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Sue Goldstein
White Plains, NY [log in to unmask]
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