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Date: | Fri, 24 Sep 2010 18:39:44 -0700 |
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Hi Trish,
As a type II diabetic you have little risk of developing ketoacidosis.
Here is a direct quote from a paper by Anssi H. Manninen that appeared
in Journal of the International Society of Sports Nutrition. 1(2):7-11,
2004. (www.sportsnutritionsociety.org) under the title "METABOLIC
EFFECTS OF THE VERY-LOW-CARBOHYDRATE DIETS: MISUNDERSTOOD “VILLAINS” OF
HUMAN METABOLISM"
DIABETIC KETOACIDOSIS VS. DIETARY KETOSIS
Diabetic patients know that the detection in their urine of the ketone
bodies is a danger signal that their diabetes is poorly controlled.
Indeed, in severely uncontrolled diabetes, if the ketone bodies are
produced in massive supranormal quantities, they are associated with
ketoacidosis. In this life-threatening complication of diabetes
mellitus, the acids 3-hydroxybutyric acid and acetoacetic acid are
produced rapidly, causing high concentrations of protons, which
overwhelm the body’s acid-base buffering system. However, during very
low carbohydrate intake, the regulated and controlled production of
ketone bodies causes a harmless physiological state known as dietary
ketosis. In ketosis, the blood pH remains buffered within normal limits.
Ketone bodies have effects on insulin and glucagon secretions that
potentially contribute to the control of the rate of their own formation
because of antilipolytic and lipolytic hormones, respectively. Ketones
also have a direct inhibitory effect on lipolysis in adipose tissue.
Interestingly, the effects of ketone body metabolism suggest that mild
ketosis may offer therapeutic potential in a variety of different common
and rare disease states . The large categories of disease for which
ketones may have therapeutic effects are: 1) diseases of substrate
insufficiency or insulin resistance; 2) diseases resulting from free
radical damage; and 3) disease resulting from hypoxia.
This is an unfortunate myth that has its roots in many medical students
being taught that the terms ketosis and ketoacidosis are the same thing.
I hope that helps.
best wishes,
Ron
--
PK
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