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Date: | Tue, 10 Jun 2008 18:25:30 -0500 |
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<<Disclaimer: Verify this information before applying it to your situation.>>
I am just passing along an article someone sent me that I thought was
interesting...
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Connection Found between Celiac Disease and Hashimoto's Thyroiditis
Celiac.com 04/23/2007 -
The results of a recent Dutch study published in the World Journal of
Gastroenterology have confirmed a connection between Hashimotos
Thyroiditis and celiac disease.
In the study, 104 individuals with Hashimotos Thyroiditis were tested
for immunoglobulin A anti-transglutaminase (tTG) antibodies, IgA
anti-endomysial antibodies (EMA) and HLA-DQ typing. Those who tested
positive for any of the serological tests were given an intestinal
biopsy.
Sixteen patients (15%) showed positive celiac serology and five
patients clear villous atrophy were diagnosed with celiac disease
(4.8%; 95% CI 0.7-8.9). All five patients diagnosed with celiac
disease, and 53 patients with Hashimotos thyroiditis (50%; 95% CI
43-62), showed the presence of HLA-DQ2 (and/or -DQ8).
In a separate test within the study, 184 Individuals with known celiac
disease were given a serological test for thyroglobulin and thyroid
peroxidase Antibodies, after first being given thyroid biochemical, a
thyroxine-free thyroid stimulating hormone.
39 patients (21%) showed positive thyroid serology. According to
thyroid biochemistry results, ten patients showed euthyroidism (5%;
95% CI 2-9), seven showed sub-clinical hypothyroidism (3.8%; 95% CI
1.8-7.6), and 22 patients showed overt hypothyroidism, Hashimotos
thyroiditis (12%; 95% CI 8-16). Furthermore, four patients with celiac
disease had Graves disease (2%; 95% CI 0.8-5) and one patient had
post-partum thyroiditis.
The study concludes that there is a clear association between
Hashimotos thyroiditis and celiac disease. Accordingly, it is
recommended that patients with Hashimotos thyroiditis be screened for
celiac disease and that patients with known celiac be screened for
Hashimotos thyroiditis.
World Journal of Gastroenterology 2007; 13(10).
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