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> [Original Message]
> From: Michai Freeman <[log in to unmask]>
> To: <undisclosed-recipients:>
> Date: 6/6/2006 4:28:47 PM
> Subject: [berkeley-disabled] New colonoscopy technology in the near future
>
> In the near future many people with disabilities who are not able to
> undergo an colonoscopy will be able to have one safely. This is
> encouraging news and I hope the new scan continues to be efficacious.
>
> Michai Freeman
>
> Michai Freeman, CEO
> Glad To Be Here Inc.
> P.O.Box 12124
> Berkeley, CA 94712
> PH: 510-326-8718
> FAX : 510-548-4479
> www.gladtobehere.org
>
> COMPUTER-AIDED POLYP DETECTION SOFTWARE IN COMBINATION WITH VIRTUAL
> COLONOSCOPY IS AS EFFECTIVE AS TRADITIONAL OPTICAL COLONOSCOPY
>
> A study led by the National Institutes of Health Clinical Center finds
> that computer-aided detection (CAD) software in conjunction with a
> procedure commonly called virtual colonoscopy can deliver results
> comparable to conventional optical colonoscopy for detecting the most
> worrisome types of polyps.
>
> The study is published in the December 2005 issue of the American
> Gastroenterological Association journal, "Gastroenterology". The work
> also was presented November 29, 2005 at the annual meeting of the
> Radiological Society of North America.
>
> Virtual colonoscopy (CT colonography) is a minimally invasive
> radiological procedure. The colon is viewed using a CT scan so there is
> no need for sedation or insertion of a colonoscope, but a full bowel
> prep still is required. Virtual colonoscopy is under investigation as a
> screening method for colorectal cancer, which is the second leading
> cause of cancer death in America.
>
> "Proper screening can prevent colorectal cancer. It is important for the
> scientific and medical community to explore and perfect methods that may
> encourage more people to get checked," says Ronald M. Summers, M.D.,
> Ph.D., the lead author of the study. Dr. Summers is a senior
> investigator and staff radiologist at the NIH Clinical Center. He is the
> chief of the clinical image processing service and chief of the virtual
> endoscopy and computer-aided diagnosis laboratory in the Department of
> Radiology.
>
> Virtual colonoscopy uses a CT scan to create two- and three-dimensional
> images of the colon. The process produces 600 to 1,000 images that are
> interpreted by a radiologist. Computer-aided detection software then
> serves as a second set of eyes and identifies sites that warrant closer
> inspection. The radiologist again reviews these sites to make the final
> diagnosis.
>
> This study set out to assess the performance and sensitivity of CAD for
> virtual colonoscopy in a large screening group of patients with no
> symptoms of colorectal cancer.
>
> After training the CAD system on the virtual colonoscopies of a separate
> group of 394 patients, Dr. Summers and his colleagues used the CAD
> system on 792 patients at three medical centers. In one day, the
> patients underwent both virtual colonoscopy and conventional optical
> colonoscopy which is considered the gold standard for screening. The
> procedures were done to detect adenomas, benign growths that may become
> cancerous if not removed.
>
> When CAD was applied to each CT colonography scan, it detected 89.3
> percent of patients having adenomas 10mm or larger, compared to 85.7
> percent for conventional colonoscopy. CAD detected 85.4 percent of
> patients having adenomas 8mm or larger, compared to 89.6 percent for
> conventional colonoscopy. CAD's false positive rates were 2.1 false
> positive detections per patient for polyps 10 mm or greater and 6.7
> false positive detections per patient for polyps 8 mm or greater. A
> review of the false positives led the researchers to conclude that most
> would be easily identifiable as such.
>
> CAD detected cancer in two patients while optical colonoscopy initially
> detected only one. The colonoscopist found the second cancer after
> getting word that virtual colonoscopy had detected an abnormality.
>
> "The fact that this worked so well on a large number of patients
> indicates that this is a robust technique," says Dr. Summers. "We
> believe it will work well in clinical practice, but more testing in the
> clinical environment still is needed."
>
> "Research into better ways to screen for and prevent disease is an
> important aspect of NIH's clinical research mission," says John I.
> Gallin, M.D., director of the NIH Clinical Center. "Studies like this
> demonstrate how collaboration enriches research. We appreciate the
> contribution of patients, who are our partners in research, and the
> teamwork of our colleagues."
>
> Screening patients came from National Naval Medical Center in Bethesda,
> Maryland, Walter Reed Army Medical Center in Washington, D.C. and San
> Diego Naval Medical Center.
>
> This study was done in conjunction with researchers from the National
> Naval Medical Center, Walter Reed Army Medical Center and Uniformed
> Services University of the Health Sciences in Bethesda, Maryland.
> Jianhua Yao, Ph.D., Perry J. Pinkhardt, M.D., Marek Franaszek, Ph.D.
> Ingmar Bitter, Ph.D., Daniel Brickman, B.S., Vamsi Krishna, B.A., J.
> Richard Choi, ScD, M.D participated in the study.
>
> The NIH Clinical Center is the clinical research hospital of the
> National Institutes of Health. Through clinical research, physicians and
> scientists translate laboratory discoveries into better treatments,
> therapies and interventions to improve the nation's health.
>
>
>
>
> [Non-text portions of this message have been removed]
>
>
>
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