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Mon, 18 Jun 2001 14:51:10 -0400 |
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On Mon, 18 Jun 2001, siobhan wrote:
> Here are the reference sources I used to make this statement:
>
> 1) Clinical Applications of Fatty Acid Profiling; Richard S. Lord, Ph.D and
> J. Alexander Bralley, Ph.D., C.C.N.
>
> " Stearic acid is a saturated fatty acid. It is two carbon atoms longer
> than palmitic acid and is similarly cholesterogenic..."
I think this claim is disputed. See for example
http://www.hhdev.psu.edu/research/Stearic.htm From what I have
read recently, stearic acid appears to be neutral in its effect
on cholesterol.
> " Abnormal levels in erythrocyte membranes cause alteration in membrane
> fluidity. Increased fluidity is associated with active tumor
> proliferation."
Stearic acid in membranes would tend to *decrease* fluidity.
> 2) Persad RA, Hillatt DA, Heinemann D, et al. Erythrocyte stearic to oleic
> acid ratio in prostatic carcinoma.
>
> " The ratio of stearic to oleic acids in red cell membranes has been found
> to be a strong indicator of the presence of malignant tissue as it reflects
> the lowered ratio found in malignant tissue cell membranes."
Yes, but they don't say (here) which way the ratio works. The
above quotation suggests that a *lower* ratio of stearic to oleic
acid in membranes is indicative of malignancy. In neither case
is their any indication of a causal role, incidentally.
Todd Moody
[log in to unmask]
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